Arizona Cardinals
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Questionable against San Francisco
Fri, Sep 25, 2026, 7:39 PM
Lopez (groin) is listed as questionable for Sunday's game versus the 49ers, Darren Urban of the Cardinals' official site reports.
Analysis: Lopez has been dealing with the groin issue for a few weeks. He didn't practice Wednesday or Thursday, and while he was limited during Friday's session, he is still considered questionable to play in Week 3. If Lopez isn't available against the 49ers, Andrew Billings may take on as much work as he can handle.
No injury designation for Week 3
Fri, Sep 25, 2026, 7:34 PM
Williams (Achilles) does not carry an injury designation ahead of Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
Analysis: Williams hasn't played yet this season while working his way back from a torn Achilles that he suffered in December of 2025. He was limited in practice Wednesday and Thursday. However, the 25-year-old was a full participant Friday. While Williams might be eased back into action for a week or two, he could be in line for as many snaps as he can handle, considering Will Johnson (neck) isn't expected to play again this season.
Questionable versus 49ers
Fri, Sep 25, 2026, 7:29 PM
Melton (toe) is listed as questionable for Sunday's game versus San Francisco, Darren Urban of the Cardinals' official site reports.
Analysis: Melton didn't practice Wednesday and was limited Thursday and Friday. He's now considered questionable for the Week 3 meeting with the 49ers. Garrett Williams (Achilles) doesn't hold an injury designation, so his availability will help lessen the blow if Melton can't get on the field.
Won't play in Week 3
Fri, Sep 25, 2026, 7:28 PM
Taylor-Demerson (back) is listed as out for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
Analysis: Taylor-Demerson didn't practice Wednesday but was limited Thursday, indicating he was making progress toward being available in Week 3. However, he took a step backward by not practicing again Friday, resulting in his second absence of the 2026 campaign. Without Taylor-Demerson in the mix Sunday, Wydett Williams may need to be more involved.
Limited in Thursday's practice
Thu, Sep 24, 2026, 10:06 PM
Melton (toe) was a limited participant in Thursday's practice.
Analysis: It's a step in the right direction for Melton, who missed Wednesday's practice due to a toe injury he sustained during the Cardinals' Week 2 loss to the Seahawks. The Cardinals will announce injury designations following Friday's practice, at which point Melton's status for Sunday's game against the 49ers will be more clear.
Returns to practice Thursday
Thu, Sep 24, 2026, 10:04 PM
Taylor-Demerson (back) was a limited participant in Thursday's practice.
Analysis: Taylor-Demerson missed Wednesday's practice due to a back injury he likely picked up in the Cardinals' Week 2 loss to the Seahawks. His ability to return to practice Thursday is a positive sign in his injury progression, and Friday's injury report will provide more clarity on Taylor-Demerson's status heading into Sunday's game against the 49ers.
Misses practice Wednesday
Wed, Sep 23, 2026, 9:12 PM
Melton (toe) did not participate at the Cardinals' practice Wednesday, Josh Weinfuss of ESPN.com reports.
Analysis: Melton suffered a toe injury during the team's 31-7 loss to Seattle in Week 2, and he is considered day-to-day. The cornerback will have two more chances to return to practice prior to Sunday's matchup with the 49ers. If he can't play this week, Kalen King would be a top candidate to draw a start at slot cornerback versus San Francisco.
Limited to open week
Wed, Sep 23, 2026, 9:08 PM
Williams (Achilles) was a limited participant at the Cardinals' practice Wednesday, Josh Weinfuss of ESPN.com reports.
Analysis: Williams has yet to make his season debut as he continues to work his way back from an Achilles injury he suffered in December, but he appears to be nearing a return to action. With fellow cornerback Will Johnson (neck) expected to miss the remainder of the 2026 campaign, Williams will have a chance to step into a starting role once he's healthy. The 25-year-old will have two more opportunities to log a full practice before Sunday's matchup with San Francisco.
Misses practice Wednesday
Wed, Sep 23, 2026, 9:01 PM
Taylor-Demerson (back) did not participate at the Cardinals' practice Wednesday, Josh Weinfuss of ESPN.com reports.
Analysis: Taylor-Demerson is dealing with an apparent back injury after he played two defensive snaps and 15 snaps on special-teams during the team's 31-7 loss to the Seahawks in Week 2. The safety will have two more chances to return to practice before Sunday's matchup with the 49ers.
Not included on injury report
Wed, Sep 23, 2026, 8:54 PM
Billings (knee) did not appear on the Cardinals' injury report Wednesday, Josh Weinfuss of ESPN.com reports.
Analysis: Billings was unable to play in Sunday's 31-7 loss to the Seahawks after suffering a knee injury earlier in the week, but he now appears to be back to full health. The 31-year-old will likely be back in his role as a primary reserve option behind Roy Lopez (groin) and Walter Nolen at defensive tackle versus San Francisco in Week 3.
Signed to active roster
Wed, Sep 23, 2026, 7:20 PM
The Cardinals signed Thomas to the active roster from their practice squad Wednesday, Darren Urban of the team's official site reports.
Analysis: Thomas appeared in 17 games for Arizona during the 2024 campaign and logged 47 tackles (31 solo) and a forced fumble, but he missed the entirety of last season due to a torn ACL. With Will Johnson expected to miss the remainder of the season due to a neck injury, Thomas should provide additional depth at corner to help fill the void.
Lands on IR, not expected back this season
Wed, Sep 23, 2026, 5:14 PM
The Cardinals placed Johnson (neck) on injured reserve Wednesday, Darren Urban of the team's official site reports.
Analysis: Johnson suffered a neck injury in the 31-7 loss to the Seahawks in Week 2. He was placed on injured reserve, so he is guaranteed to miss at least four games. However, the 23-year-old isn't expected to play again this season. If that's the case, he will finish the year with eight total tackles (three solo), one fumble recovery and one pass defended. Without Johnson, Garrett Williams (Achilles), who has yet to play this season, could take on a larger role upon his return. Max Melton (toe), Kei'Trel Clark and Starling Thomas, the latter who was promoted from the practice squad, may also be more involved.
Nine tackles in loss
Tue, Sep 22, 2026, 9:31 PM
Wilson recorded nine tackles (four solo) in Sunday's loss to the Seahawks.
Analysis: Wilson briefly exited Week 2 with a thumb injury but quickly returned and ended up playing 92.9 percent of the defensive snaps versus Seattle. After two games this season, Wilson has 15 tackles (six solo) and one pass breakup.
Piles up 11 tackles in defeat
Tue, Sep 22, 2026, 9:29 PM
Baker recorded 11 tackles (seven solo), including 1.0 sacks, and a pass breakup in Sunday's loss to the Seahawks.
Analysis: While Baker racked up a load of tackles, he was burned in coverage on Jaxon Smith-Njigba's 82-yard touchdown on a double-move in the first quarter. JSN made the entire Arizona secondary look foolish en route to 9-155-3 receiving line across 11 targets. Through two games this season, Baker has 16 tackles (11 solo), including 1.5 sacks, on 100 percent of the defensive snaps.
Kendrick Bourne
Kendrick Bourne Catches two targets in loss
Mon, Sep 21, 2026, 10:29 PM
Bourne caught two of his three targets for 11 yards in Sunday's 31-7 loss to the Seahawks.
Analysis: Bourne played 30 of the Cardinals' 50 offensive snaps in Sunday's contest. The wide receiver continues to garner some attention behind leading weapons Trey McBride and Michael Wilson while playing a significant share of the team's snaps.
Chad Ryland
Chad Ryland Barely involved in blowout loss
Mon, Sep 21, 2026, 7:23 PM
Ryland did not have any field-goal tries but converted on his only extra-point attempt during Sunday's 31-7 loss versus the Seahawks.
Analysis: In a contest where Arizona's passing attack was all but completely stifled, Ryland only got one opportunity to add to the scoreboard. It's hard for things to go much worse from a fantasy perspective, but the Cardinals have another tough matchup on tap against San Francisco in Week 3.
Avoids major injury
Mon, Sep 21, 2026, 6:20 PM
Melton (toe) is considered to be day-to-day ahead of Week 3, Howard Balzer of USA Today reports.
Analysis: Melton sustained a toe injury on his left foot in the second half of the team's 31-7 loss to Seattle on Sunday, and he was unable to return to the contest. He appears to have avoided a major injury, and his status at practice Wednesday will shed a better light on his chances to play Week 3 at San Francisco.
Could be set for long-term absence
Mon, Sep 21, 2026, 6:17 PM
Johnson (neck) may be forced to miss the remainder of the 2026 season, Darren Urban of the Cardinals' official site reports.
Analysis: Johnson suffered a neck injury in the second half of Sunday's 31-7 loss to the Seahawks, and he was unable to return to the contest. Head coach Mike LaFleur outlined Monday that it is a significant injury for the cornerback, placing doubt on his availability for the rest of the campaign. In Johnson's absence, Garrett Williams (Achilles) will likely start opposite of Denzel Burke in Arizona's secondary, once healthy.
Tyler Allgeier
Tyler Allgeier Seven touches in loss
Sun, Sep 20, 2026, 10:12 PM
Allgeier turned five carries into 10 yards and caught both of his targets for nine yards in Sunday's 31-7 loss to the Seahawks.
Analysis: Allgeier saw a substantial reduction in his rush attempts in Week 2, going from 17 carries Week 1 versus the Chargers to only having five in Sunday's blowout loss. The running back and the rest of Arizona's offense never found any sort of sustained success against Seattle, so he was far from being the only disappointing player in the contest. Notably, rookie first-rounder Jeremiyah Love garnered four more carries and reeled in one more catch than Allgeier, and the latter figures to fade into a No. 2 role as the season progresses.
Jacoby Brissett
Jacoby Brissett Ineffective against Seattle
Sun, Sep 20, 2026, 7:52 PM
Brissett completed 17 of 28 passes for 95 yards with a touchdown and an interception while also adding a seven-yard rush in Sunday's 31-7 loss to Seattle.
Analysis: Brissett struggled to push the ball down the field against the Seahawks' vaunted secondary, and as a result, he was limited to just 5.4 yards per completion. The quarterback was able to connect with tight end Trey McBride for a two-yard score to open the second quarter, but that was the only bright spot on the day for the 33-year-old. He attempted to find wide receiver Michael Wilson deep down the left sideline in the third quarter, but Julian Love jumped in front of it for his the safety's second interception of the year. Brissett has proven to be more than capable of producing positive results for fantasy managers in his time with the Cardinals, and his next chance to get back on track will come Week 3 against the 49ers on the road.

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